Christopher Rollston examines the Qeiyafa Ostracon, Gezer Calendar and other candidates for the oldest known Hebrew inscription

Using letter order in the ancient Hebrew alphabet for clues

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When a single RIF (Radiation Induced Foci) is faced with multiple DSB's (Double Strand Break in DNA), it can end up rejoining the wrong ends, creating a possibly viable misrepair. A few of the viable mutations will escape our immune system, and a few of those could become cancerous.

If double DSB's are the real problem, then dose rate and repair time becomes all important. The probability that a hit will cause a DDSB is proportional to the inventory of still unrepaired DSB's at the time of the hit.3 To over-simplify, if the repair processes can keep up with the damage, and keep that inventory low, we are OK. If the damage rate is higher than the repair rate, the inventory of unrepaired DSB's will build up, and the probability of a DDSB and a misrepair will grow rapidly. //

If we conservatively assume 10 metabolic DSB's per cell-day, and 0.04 DSB's per millisievert then it would take 250 mSv per day to equal the number of DSB's produced by our metabolism. 250 mSv is about 25,000 times normal background radiation. If normal metabolic damage is equivalent to 250 mSv/d, then any damage associated with 2 mSv/d would almost certainly not be detectable. At the same time, it is not surprising that we start to detect harm at 20 or so mSv/d. At that point, the cell is forced to deal with a substantially higher than normal number of DSB's. ///

Nature has equipped us with a remarkably effective DNA repair system. She had to do this because our O2 based metabolism damages our DNA at a rate that is more than 25,000 times the damage rate from average background radiation.

We begin our Christian life by believing what we are told to believe, then we have to go on to so assimilate our beliefs that they work out in a way that redounds to the glory of God. The danger is in multiplying the acceptation of beliefs we do not make our own.
Conformed to His Image, 381 L

Jesus Christ did not say — “Go and save souls” (the salvation of souls is the supernatural work of God), but — “Go and teach,” i.e., disciple, “all nations,” and you cannot make disciples unless you are a disciple yourself. When the disciples came back from their first mission, they were filled with joy because the devils were subject to them, and Jesus said — “Don’t rejoice in successful service; the great secret of joy is that you are rightly related to Me.” The great essential of the missionary is that he remains true to the call of God, and realises that his one purpose is to disciple men and women to Jesus.

It’s always DNS
Amazon said the root cause of the outage was a software bug in software running the DynamoDB DNS management system. The system monitors the stability of load balancers by, among other things, periodically creating new DNS configurations for endpoints within the AWS network. A race condition is an error that makes a process dependent on the timing or sequence events that are variable and outside the developers’ control. The result can be unexpected behavior and potentially harmful failures.

In this case, the race condition resided in the DNS Enactor, a DynamoDB component that constantly updates domain lookup tables in individual AWS endpoints to optimize load balancing as conditions change. As the enactor operated, it “experienced unusually high delays needing to retry its update on several of the DNS endpoints.” While the enactor was playing catch-up, a second DynamoDB component, the DNS Planner, continued to generate new plans. Then, a separate DNS Enactor began to implement them.

The timing of these two enactors triggered the race condition, which ended up taking out the entire DynamoDB.

The man’s family told doctors that, up until a few months prior, he had been taking three different types of herbal supplements that claim to treat joint pain. The man had taken the supplements for four years, and sometimes as often as four times a day, but he had stopped using them in the lead-up to his illness.

Deadly doses
The supplements were: Artri King, Nhan Sam Tuyet Lien, and Linsen Double Caulis Plus. All are known to contain unlisted glucocorticoids, according to the Food and Drug Administration. And testing of two of the man’s supplements by the hospital confirmed the presence of the steroids.

Doctors determined that the man had essentially overdosed on the glucocorticoids—he had taken doses that exceeded the normal levels of glucocorticoids in the body. The steroids likely suppressed immune responses, leading to his infections and GI ulcers. But, more significantly, the excess steroid levels also caused his HPA axis to essentially shut down. While it’s possible to get the HPA axis back up and running after withdrawal from excessive steroid use, the amount of time that takes can vary. Further, if a person stops taking large doses of glucocorticoids abruptly, rather than gradually—as in the man’s case—and particularly after chronic use—also as in the man’s case—it can lead to an adrenal crisis. In retrospect, the man had all the signs of a crisis.

If we ID the DNA for a great antibody, anyone can now make it. //

knowing what antibodies we’d like to see people making while having no way of ensuring that they do.

One of the options we’ve developed is to just mass-produce broadly neutralizing antibodies and inject them into people. This has been approved for use against Ebola and provided an early treatment during the COVID pandemic. This approach has some practical limitations, though. For starters, the antibodies have a finite life span in the bloodstream, so injections may need to be repeated. In addition, making and purifying enough antibodies in bulk isn’t the easiest thing in the world, and they generally need to be kept refrigerated during the distribution, limiting the areas where they can be used.

So, a number of companies have been looking at an alternative: getting people to make their own. This could potentially lead to longer-lived protection, even ensuring the antibodies are present to block future infections if the DNA survives long enough.

When the Emir of Qatar’s Boeing 747-8 BBJ touched down in Palma at the end of June 2025, it brought with it a rare sight and a logistical challenge. The aircraft, often called a flying palace, is one of the largest and most extravagant private jets ever built. Its arrival marked the beginning of the Qatari royal family’s annual summer stay in Spain, a tradition that combines opulence with routine.

On June 30, 1973, a supersonic jet screamed across the African sky at 58,000 feet, chasing darkness at 1,450 miles per hour. Inside Concorde 001, seven scientists peer through holes cut in the roof, watching the longest solar eclipse in human history unfold. //

Over Africa, the Moon’s shadow raced across Earth at over 1,300 miles per hour. Ground observers got seven minutes before the shadow moved on. But Concorde at Mach 2.2 could actually outrun the shadow, staying locked in totality for as long as fuel lasted. //

Height mattered as much as speed. At 58,000 feet, the aircraft flew above weather, water vapor, and atmospheric turbulence that would blur ground observations. The combination of speed, altitude, and precise navigation created a stable observatory hurtling through space faster than a rifle bullet.

Supersonic cruise generated fierce aerodynamic heating, raising the skin to temperatures that would alarm passengers on any other jet. At the nose, engineers recorded figures as high as 261°F (127°C). The wing leading edges often reached about 212°F (100–105°C), while most of the fuselage settled between 194 and 203°F (90–95°C). //

At those temperatures, the entire 202-foot Concorde stretched by 7 to 12 inches. That expansion was most visible to the crew at the seam beside the engineer’s station, where the caps went in. //

The ritual of sealing a cap in the fuselage became most famous during the retirement era. On British Airways Concorde G-BOAG’s delivery flight to Seattle in 2003, flight engineer Trevor Norcott slipped his BA cap into the expansion gap while supersonic over Canada. As he later explained, “The Hat was meant as a permanent link between the aircraft and the crews.” Hours later, as the jet cooled on the ramp in Seattle, the seam clamped down, locking the cap inside. To this day, visitors walking past G-BOAG at the Museum of Flight unknowingly pass a hidden time capsule wedged between metal panels.

A rare shot shows the Concorde taking off with the NASA 905 carrying the Space Shuttle

The British historical novelist C. S. Forester is best known as the creator of Horatio Hornblower, whose rise from midshipman to admiral and peer during the Napoleonic Wars is told in a series of twelve novels, beginning with ‘The Happy Return’. Two of the Hornblower novels, ‘A Ship of the Line’ and ‘Flying Colours’, were jointly awarded the James Tait Black Memorial Prize for fiction in 1938. This comprehensive eBook presents Forester’s collected works, with numerous illustrations, rare texts, informative introductions and the usual Delphi bonus material. (Version 2)

Please note: the eBook is only for sale to customers living in or visiting Canada, China, Hong Kong, Pakistan, New Zealand, South Africa, Thailand and any other 50 year countries due to copyright restrictions.

The Gilwell Park Weather Rock always has the up to the minute weather conditions and has been placed here for your convenience.

The Official Weather Rock is located on Gilwell field and may be used in the following manner:

First -- Observe the rock for motion

The Rock is not moving- 0-3 MPH ligh breeze
The Rock is moving slightly - 4-10 MPH Mild wind
The Rock is moving in a small arc - 11 to 20 MPH Wind
The Rock is moving in a medium arc - 21 to 40 MPH Wind-Gusts to 50 MPH
The Rock is standing off to one side by 15' - Gale Force Winds
The Rock is standing off to one side by 30-45' - Big Blow Coming
The Rock is standing off to one side by 60'-Hurricane!!
The Rock is standing at 90'-Tornado!! Get to a root cellar! Take Toto!
The Rock is bouncing up and down-Earthquake !!
Second - Touch and Look at the Rock

The Rock is cold, dry and easy to see- Clear, Fair Weather, it's Cold
The Rock is cool, dry and easy to see- Overcast Weather
The Rock is warm, dry and easy to see- Clear, Fair Weather
The Rock has a shadow - It's sunny
The Rock is hot & dry and easy to see - Clear Weather, It's Hot
The Rock is warm and white - Chase the birds away
The Rock is cold, wet and easy to see-It's a cold, wet, day-Dress warm
The Rock is wet on top and dry on the bottom- It's Sprinkling
The Rock is cool,wet, and easy to see-It's rainging. Get your poncho.
The Rock is dripping on all sides-Its a downpour-Too late for poncho

A case of oops rather than UPS

Sorry, couldn't resist. I'd better be going

That was a powerful joke

The sort of thing that could spark a pun-off: a current trend at El Reg.

We Volted at the chance to have some pun

A landmark work of over 100 scholars, The Heritage Guide to the Constitution provides unique line-by-line analysis explaining every clause of America's founding charter and its contemporary meaning. Second edition completely revised.

• An unprecedented collaborative work of 114 leading scholars, with over 200 original essays
• Completely revised, nine years following the original landmark work
• Foreword by Edwin Meese III, 75th Attorney General of the United States

calibre has a binary install that includes private versions of all its dependencies. It runs on 64-bit Intel or ARM compatible machines. To install or upgrade, simply copy and paste the following command into a terminal and press Enter:

sudo -v && wget -nv -O- https://download.calibre-ebook.com/linux-installer.sh | sudo sh /dev/stdin

sudo apt install libxkbcommon0

Regular expressions are features used in many places in calibre to perform sophisticated manipulation of e-book content and metadata. This tutorial is a gentle introduction to getting you started with using regular expressions in calibre.

Start the calibre Content server. The calibre Content server exposes your calibre libraries over the internet. You can specify the path to the library folders as arguments to calibre-server. If you do not specify any paths, all the libraries that the main calibre program knows about will be used.